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Biochemistry

Molecule diagram

Jöns Jacob Berzelius, in the preface (addressed to Gustav IV Adolf) to the first Swedish edition of Animal Chemistry, 1806, said: "Of all the sciences contributing to medicine, chemistry is the primary one, and, apart from the general light it throws on the entire art of healing, it will soon bestow on some of its branches a perfection such as one never could have anticipated." To this day, Biochemistry provides the interface between the living and non-living worlds. The goals of the Biochemistry research faculty in the Department of Biological Sciences are to understand the molecular mechanisms underlying biological processes, and o examine the relationships between structure and function in biological macromolecules. Our interests include the mechanisms of action of both protein and RNA catalysts, and our studies require state-of-the-art methods ranging from X-ray crystallography, steady-state and single turnover kinetics, protein and nucleic acid purification and analysis, and mathematical modeling.


Karen Arndt

Karen Arndt
Transcriptional Control

Andrea J. Berman

Andrea J. Berman
RNA Biology

Jeffrey L. Brodsky

Jeffrey L. Brodsky
Protein Quality Control

Laty Cahoon

Laty Cahoon
Host-Pathogen Interactions

Jacob Durrant

Jacob Durrant
Computer-Aided Drug Design

Graham Hatfull

Graham Hatfull
Phages and Tuberculosis

Kirill Kiselyov

Kirill Kiselyov
Ion Channel Function

Anthony Schwacha

Anthony Schwacha
DNA Replication

Andrew VanDemark

Andrew VanDemark
Structural Biology