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Juan Ramiro Diaz

  • Teaching Associate Professor

Graduated in 2010 from Universidad Autonoma de San Luis Potosi (Mexico) with a PhD in Basic Biomedical Sciences. I held postdoctoral fellowships at the University of New Mexico, the University of Iowa, and Augusta University. My area of expertise is Cardiovascular Physiology. Over the years, my research was focused on determining: 

·                     The mechanism of blood flow detection in the coronary circulation.  

·                     The role of the transcription factor NFATc3 in hypoxia-induced pulmonary hypertension. 

·                     The role of endothelial CaMKII in the progression of diabetic retinopathy. 

·                     The regulatory mechanisms of blood flow and neuronal activity mediated by the reciprocal interactions of the neurovascular unit. 

    Education & Training

  • Universidad Autonoma de San Luis Potosi (Mexico) with a PhD in Basic Biomedical Sciences
Representative Publications

Representative research publications: 

·                     Augmented astrocyte microdomain Ca2+ dynamics and parenchymal arteriole tone in angiotensin II‐infused hypertensive mice. JR Diaz, KJ Kim, MW Brands, JA Filosa. Glia 67 (3), 551-565. 

·                     Vasculo-neuronal coupling: retrograde vascular communication to brain neurons. KJ Kim, JR Diaz, JA Iddings, JA Filosa. Journal of Neuroscience. 36 (50), 12624-12639. 

·                     Endothelial CaMKII as a regulator of eNOS activity and NO-mediated vasoreactivity. S Murthy, OM Koval, JM Ramiro Diaz, S Kumar, D Nuno, JA Scott, Chantal Allamargot, Linda J Zhu, Kim Broadhurst, Velarchana Santhana, William J Kutschke, Kaikobad Irani, Kathryn G Lamping, Isabella M Grumbach. PloS one 12 (10), e0186311 

·                     NFAT is required for spontaneous pulmonary hypertension in superoxide dismutase 1 knockout mice. JM Ramiro-Diaz, CH Nitta, LD Maston, S Codianni, W Giermakowska, Thomas C Resta, Laura V Gonzalez Bosc. American Journal of Physiology-Lung Cellular and Molecular Physiology 304 (9, L613-L625). 

·                     Luminal endothelial lectins with affinity for N-acetylglucosamine determine flow-induced cardiac and vascular paracrine-dependent responses. J Ramiro-Diaz, A Barajas-Espinosa, E Chi-Ahumada, S Perez-Aguilar, David Torres-Tirado, Jesus Castillo-Hernandez, Maureen Knabb, Ana Barba De La Rosa, Rafael Rubio. American Journal of Physiology-Heart and Circulatory Physiology, 299 (3, H743-H751). 

Research Interests

Academic publications: 

·                     Anatomy and Physiology I: An Interactive Histology Atlas. Karen Wiles; Christina Wilson; Juan Manuel Ramiro-Diaz; Georgios Kallifatidis; and Soma Mukhopadhyay. 
https://pressbooks.pub/aandp1histologyatlasandworkbook/  
 

·                     Anatomy and Physiology II: An Interactive Histology Atlas. Juan Manuel Ramiro Diaz; Karen Wiles; Georgios Kallifatidis; Christina Wilson; and Soma Mukhopadhyay. 
https://pressbooks.pub/aandp2histologyatlas/