Welkin Pope

  • Research Assistant Professor


Office: (412) 624-3921
367 Crawford Hall
4249 Fifth Avenue
Pittsburgh, PA 15260

I am interested in the physical and genomic characterization of bacteriophages, specifically phage-host interactions and dynamics. I work with Mycobacterium, Gordonia, CorynebacteriumBacillus sp., and marine Synechococcus as host organisms for recovering new isolates from all parts of the globe. I am also interested in using bacteriophage analysis as a vehicle for authentic research with undergraduates both in and out of the classroom.

Pope WH, Hatfull GF. Adding piece

Pope WH, Hatfull GF. Adding pieces to the puzzle.New insights into bacteriophage diversity from integrated research-education programs.Bacteriophage. 2015 Aug 18;5(4):e1084073. eCollection 2015 Oct-Dec.PMID:26904380

Pope WH, Bowman CA, Russell DA, J

Pope WH, Bowman CA, Russell DA, Jacobs-Sera D, Asai DJ, Cresawn SG, Jacobs WR, Hendrix RW, Lawrence JG, Hatfull GF; Science Education Alliance Phage Hunters Advancing Genomics and Evolutionary Science; Phage Hunters Integrating Research and Education; Mycobacterial Genetics Course. 2015. Whole genome comparison of a large collection of mycobacteriophages reveals a continuum of phage genetic diversity.Elife. 2015 Apr 28;4:e06416. doi: 10.7554/eLife.06416.

Cresawn, S. G., Pope, W. H., Jacobs-Sera, D., B

Cresawn, S. G., Pope, W. H., Jacobs-Sera, D., Bowman, C. A., Russell, D. A., Dedrick, R. A., Adair, T., Anders, K. R., Ball, S., Bollivar, D., Breitenberger, C., Burnett, S. H., Butela, K., Byrnes, D., Carzo, S., Cornely, K. A., Cross, T., Daniels, R. L., Dunbar, D., Findley, A. M., Gissendanner, C. R., Golebiewska, U. P., Hartzog, G. A., Hatherill, J. R., Hughes, L. E., Jalloh, C. S., DeLosSantos, C., Ekanam, K., Khambule, S. L., King, R. A., King-Smith, C., Klyczek, K., Krukonis, G. P., Laing, C., Lapin, J. S., Lopez, A. J., Mkhwanazi, S. M., Molloy, S. D., Moran, D., Munsamy, V., Pacey, E., Plymale, R., Poxleitner, M., Reyna, N., Schildbach, J. F., Stukey, J., Taylor, S. E., Ware, V. C., Wellmann, A. L., Westholm, D., Wodarski, D., Zajko, M., Zikalala, T. S., Hendrix, R. W., and  Hatfull, G. F. (2015) Comparative Genomics of Cluster O Mycobacteriophages PLoS One 10:e0118725.

Pope, W.H., Anders, K. R., Baird, M., Bowman, C

Pope, W.H., Anders, K. R., Baird, M., Bowman, C.A., Boyle, M.M., Broussard, G.W., Chow, T., Clase, K.L., Cooper, S., Cornely, K.A., Dejong, R.J., Delesalle, V.A., Deng, L., Dunbar, D., Edgington, N.P., Ferreira, C.M., Hafer, K.W., Hartzog, G.A., Hatherill, J.R., Hughes, L.E., Ipapo, K., Krukonis, G.P., Meier, C.G., Monti, D.L., Olm, M.R., Page, S.T., Peebles, C.L., Rinehart, C.A., Rubin, M.R., Russell, D.A., Sanders, E.R.,Schoer, M., Shaffer, J., Wherley, C.D.,Vazquez,E., Yuan, H., Zhang, D., Cresawn, S.G., Jacobs-Sera, D., Hendrix, R.W. & Hatfull, G. F. (2014) Cluster M mycobacteriophages Bongo, PegLeg, and Rey with unusually large repertoires of tRNA isotypes. J. Virol. 88, 2461-2480.

Pope WH, Jacobs-Sera D, Best AA, Broussard GW,

Pope WH, Jacobs-Sera D, Best AA, Broussard GW, Connerly PL, Dedrick RM, Kremer TA, Offner S, Ogiefo AH, Pizzorno MC, Rockenbach K, Russell DA, Stowe EL, Stukey J, Thibault SA, Conway JF, Hendrix RW, Hatfull GF.(2013). Cluster J Mycobacteriophages: intron splicing in capsid and tail genes. PLoS One. 8(7):e69273. doi: 10.1371/journal.pone.0069273

Jacobs-Sera, D., Marinelli, L. J., Bowman, C.,

Jacobs-Sera, D., Marinelli, L. J., Bowman, C., Broussard, G. W., Guerrero Bustamante, C., Boyle, M. M., Petrova, Z. O., Dedrick, R. M., Pope, W. H., Science Education Alliance Phage Hunters Advancing, G., Evolutionary Science Sea-Phages, P., Modlin, R. L., Hendrix, R. W., and Hatfull, G. F. (2012) On the nature of mycobacteriophage diversity and host preference. Virology 434, 187-201.

Pope, W.H., Ferreira, C.M., Jacobs-Sera, D., Benjamin, R.C., Davis, A.J., DeJong, R.J., Elgin, S.

Pope, W.H., Ferreira, C.M., Jacobs-Sera, D., Benjamin, R.C., Davis, A.J., DeJong, R.J., Elgin, S.C.R., Guilfoile, F.R., Forsyth, M.H., Harris, A.D., Harvey, S.E., Hughes, L.E., Hynes, P.M., Jackson, A.S., Jalal, M.D., MacMurray, E.A., Manley, C.M., McDonough, M.J., Mosier, J.L., Osterbann, L.J., Rabinowitz, H.S., Rhyan, C.N., Russell, D.A., Saha, M.S., Shaffer, C.D., Simon, S.E., Sims, E.F., Tovar, I.G., Weisser, E.G., Wertz, J.T., Weston-Hafer, K.A., Williamson, K.E., Zhang, B., Cresawn, S.G., Jain, P., Piuri, M., Jacobs, W.R., Jr., Hendrix, R.W. and Hatfull, G.F. (2011) Cluster K Mycobacteriophages: Insights into the Evolutionary Origins of Mycobacteriophage TM4. PLoS ONE 6:e26750.

Pope, W.H., D. Jacobs-Sera, D.A. Russell, C.L. Peebles, Z. Al-Atrache, T.A. Alcoser, L.M. Alexand

Pope, W.H., D. Jacobs-Sera, D.A. Russell, C.L. Peebles, Z. Al-Atrache, T.A. Alcoser, L.M. Alexander, M.B. Alfano, S.T. Alford, N.E. Amy, M.D. Anderson, A.G. Anderson, A.A. Ang, J.r Ares M, A.J. Barber, L.P. Barker, J.M. Barrett, W.D. Barshop, C.M. Bauerle, I.M. Bayles, K.L. Belfield, A.A. Best, J.r Borjon A, C.A. Bowman, C.A. Boyer, K.W. Bradley, V.A. Bradley, L.N. Broadway, K. Budwal, K.N. Busby, I.W. Campbell, A.M. Campbell, A. Carey, S.M. Caruso, R.D. Chew, C.L. Cockburn, L.B. Cohen, J.M. Corajod, S.G. Cresawn, K.R. Davis, L. Deng, D.R. Denver, B.R. Dixon, S. Ekram, S.C. Elgin, A.E. Engelsen, B.E. English, M.L. Erb, C. Estrada, L.Z. Filliger, A.M. Findley, L. Forbes, M.H. Forsyth, T.M. Fox, M.J. Fritz, R. Garcia, Z.D. George, A.E. Georges, C.R. Gissendanner, S. Goff, R. Goldstein, K.C. Gordon, R.D. Green, S.L. Guerra, K.R. Guiney-Olsen, B.G. Guiza, L. Haghighat, G.V. Hagopian, C.J. Harmon, J.S. Harmson, G.A. Hartzog, S.E. Harvey, S. He, K.J. He, K.E. Healy, E.R. Higinbotham, E.N. Hildebrandt, J.H. Ho, G.M. Hogan, V.G. Hohenstein, N.A. Holz, V.J. Huang, E.L. Hufford, P.M. Hynes, A.S. Jackson, E.C. Jansen, J. Jarvik, P.G. Jasinto, T.C. Jordan, T. Kasza, M.A. Katelyn, J.S. Kelsey, L.A. Kerrigan, D. Khaw, J. Kim, J.Z. Knutter, C.C. Ko, G.V. Larkin, J.R. Laroche, A. Latif, K.D. Leuba, S.I. Leuba, L.O. Lewis, K.E. Loesser-Casey, C.A. Long, A.J. Lopez, N. Lowery, T.Q. Lu, V. Mac, I.R. Masters, J.J. McCloud, M.J. McDonough, A.J. Medenbach, A. Menon, R. Miller, B.K. Morgan, P.C. Ng, E. Nguyen, K.T. Nguyen, E.T. Nguyen, K.M. Nicholson, L.A. Parnell, C.E. Peirce, A.M. Perz, L.J. Peterson, R.E. Pferdehirt, S.V. Philip, K. Pogliano, J. Pogliano, T. Polley, E.J. Puopolo, H.S. Rabinowitz, M.J. Resiss, C.N. Rhyan, Y.M. Robinson, L.L. Rodriguez, A.C. Rose, J.D. Rubin, J.A. Ruby, M.S. Saha, J.W. Sandoz, J. Savitskaya, D.J. Schipper, C.E. Schnitzler, A.R. Schott, J.B. Segal, C.D. Shaffer, K.E. Sheldon, E.M. Shepard, J.W. Shepardson, M.K. Shroff, J.M. Simmons, E.F. Simms, B.M. Simpson, K.M. Sinclair, R.L. Sjoholm, I.J. Slette, B.C. Spaulding, C.L. Straub, J. Stukey, T. Sughrue, T.Y. Tang, L.M. Tatyana, S.B. Taylor, B.J. Taylor, L.M. Temple, J.V. Thompson, M.P. Tokarz, S.E. Trapani, A.P. Troum, J. Tsay, A.T. Tubbs, J.M. Walton, D.H. Wang, H. Wang, J.R. Warner, E.G. Weisser, S.C. Wendler, K.A. Weston-Hafer, H.M. Whelan, K.E. Williamson, A.N. Willis, H.S. Wirtshafter, T.W. Wong, P. Wu, Y. Yang, B.C. Yee, D.A. Zaidins, B. Zhang, M.Y. Zuniga, R.W. Hendrix, and G.F. Hatfull (2011) Expanding the diversity of mycobacteriophages: insights into genome architecture and evolution. PLoS One 6:e16329e16329

Mageeney, C., W. Pope, M. Harrison, D. Moran, T

Mageeney, C., W. Pope, M. Harrison, D. Moran, T. Cross, D. Jacobs-Sera, R. W. Hendrix, D. Dunbar & G. F. Hatfull, (2012) Mycobacteriophage Marvin: A new singleton phage with an unusual genome organization. J Virol. 86:4762-75.

Weigele, P.R., W.H. Pope, M.L. Pedulla, J.M. Houtz, A.L. Smith, J.F. Conway, J. King, G.F. Hatful

Weigele, P.R., W.H. Pope, M.L. Pedulla, J.M. Houtz, A.L. Smith, J.F. Conway, J. King, G.F. Hatfull, J.G. Lawrence, and R.W. Hendrix (2007) Genomic and structural analysis of Syn9, a cyanophage infecting marine Prochlorococcus and Synechococcus. Environ. Microbiol. 9:1675-1695

Dr. Pope received her BS in Biology from MIT in 2000, did her graduate work in the laboratory of Prof. Jonathan King at MIT and received a PhD in 2005 from the Massachusetts Institute of Technology/Woods Hole Oceanographic Institution Joint Program in Biological Oceanography. She did post-doctoral work with Dr. Roger Hendrix and Dr. Graham Hatfull at the University of Pittsburgh and joined the faculty in 2012.

PhD MIT/WHOI Joint Program in Biological Oceanography 2005; BS Massachusetts Institute of Technology 2000

University of Pittsburgh DB-SERC Course Transformation Award, 2015